NVP 231
CAS No. 362003-83-6
NVP 231 ( NVP231; NVP 231; NVP-231 )
Catalog No. M14241 CAS No. 362003-83-6
NVP-231 is a potent, specific, and reversible CerK inhibitor(IC50=12±2 nM) that competitively inhibits binding of ceramide to CerK.
Purity : >98%(HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
Size | Price / USD | Stock | Quantity |
5MG | 27 | In Stock |
|
10MG | 43 | In Stock |
|
25MG | 70 | In Stock |
|
50MG | 113 | In Stock |
|
100MG | 186 | In Stock |
|
200MG | Get Quote | In Stock |
|
500MG | Get Quote | In Stock |
|
1G | Get Quote | In Stock |
|
Biological Information
-
Product NameNVP 231
-
NoteResearch use only, not for human use.
-
Brief DescriptionNVP-231 is a potent, specific, and reversible CerK inhibitor(IC50=12±2 nM) that competitively inhibits binding of ceramide to CerK.
-
DescriptionNVP-231 is a potent, specific, and reversible CerK inhibitor(IC50=12±2 nM) that competitively inhibits binding of ceramide to CerK.
-
SynonymsNVP231; NVP 231; NVP-231
-
PathwayMAPK/ERK Signaling
-
TargetERK
-
RecptorCERK
-
Research AreaCancer
-
Indication——
Chemical Information
-
CAS Number362003-83-6
-
Formula Weight431.55
-
Molecular FormulaC25H25N3O2S
-
Purity>98%(HPLC)
-
SolubilitySoluble in DMSO
-
SMILESO=C(C1(C2)C[C@H]3C[C@@H]2C[C@H](C3)C1)NC4=CC=C5N=C(NC(C6=CC=CC=C6)=O)SC5=C4
-
Chemical NameN -[2-(Benzoylamino)-6-benzothiazolyl]tricyclo[3.3.1.13,7]decane-1-carboxamide
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Graf C, et al.Mol Pharmacol. 2008 Oct;74(4):925-32.
molnova catalog
related products
-
ISRIB (trans-isomer)
ISRIB (trans-isomer), the trans-isomer of ISRIB, is a potent and selective PERK inhibitor with IC50 of 5 nM.
-
ASTX029
ASTX029 is a selective and orally bioavailable extracellular signal-regulated kinases 1 and 2 (ERK 1/2) inhibitor, with potential antineoplastic activity.
-
SC1
Pluripotin (SC1) is a dual inhibitor of extracellular signal-regulated kinase 1 (ERK1, MAPK3) and RasGAP. Maintains embryonic stem cell (ESC) self-renewal.